Gallbladder Surgery

Understanding Gallstones (Cholelithiasis): Symptoms, Diagnosis, and Modern Treatment

A patient-friendly guide to gallstone symptoms, diagnosis, warning signs, and when laparoscopic gallbladder surgery may be recommended.

A restrained clinical consultation placeholder

Gallstones are one of the most common digestive problems seen by general surgeons. Many people have gallstones without knowing it, while others develop severe pain or serious complications.

What are gallstones?

The gallbladder is a small organ beneath the liver. It stores bile, a fluid that helps digest fats. Gallstones form when substances in bile, mainly cholesterol or pigments, become solid and form stones.

Who is at risk?

The chance of developing gallstones may increase with:

  • age above 40 years;
  • female gender;
  • obesity;
  • pregnancy;
  • diabetes;
  • rapid weight loss; and
  • a family history of gallstones.

Gallstones can still occur in anyone, including people without these factors.

Symptoms of gallstones

Many people have no symptoms. When symptoms develop, they may include:

  • pain in the upper right side of the abdomen;
  • pain after eating fatty meals;
  • pain spreading to the back or right shoulder;
  • nausea and vomiting; and
  • indigestion.

When is it an emergency?

Seek immediate medical attention.

Fever with abdominal pain, yellow eyes or skin, severe pain lasting more than several hours, or persistent vomiting may indicate infection or blockage of the bile ducts.

How are gallstones diagnosed?

Ultrasound is the preferred first investigation because it is accurate, safe and painless. Blood tests may also be required if complications are suspected.

Treatment

Gallstones without symptoms often do not require surgery. Surgery may be recommended when gallstones cause pain or complications, depending on the patient’s clinical assessment.

Laparoscopic gallbladder removal

Laparoscopic surgery is widely used because it can offer:

  • smaller incisions;
  • less pain;
  • minimal blood loss;
  • earlier recovery;
  • a shorter hospital stay;
  • a faster return to work; and
  • better cosmetic results.

Individual recovery and suitability vary. A surgeon must assess whether this approach is appropriate for a particular patient.

Can medicines dissolve gallstones?

Medicines are useful only in selected patients and are generally much less effective than surgery for symptomatic gallstones.

Reducing the risk

Healthy eating, regular exercise, maintaining an appropriate weight and avoiding rapid weight loss may reduce the risk of gallstones.

Take Home Message

If you experience repeated pain after meals, do not ignore it. Early diagnosis and timely medical assessment can help prevent serious complications.

Clinical references and guidance

This patient information is consistent with general guidance published by:

  • World Society of Emergency Surgery
  • Society of American Gastrointestinal and Endoscopic Surgeons
  • National Institute for Health and Care Excellence
  • American College of Surgeons
  • World Health Organization
Clinical guidance should be interpreted by a qualified medical professional and may be updated over time. These organizations have not formally endorsed this article.
Your next step

Ready for a thoughtful conversation about your care?

Choose an in-person, video, voice, or second-opinion consultation.