General Surgery

Abdominal Pain: Understanding the Different Causes

A patient-friendly overview of common causes of abdominal pain by location, warning signs, and the investigations a doctor may recommend.

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Abdominal pain is one of the most common health complaints. Sometimes it is caused by simple indigestion, while in other cases it may signal a life-threatening condition.

The location of pain may help a doctor consider possible causes, but symptoms alone cannot confirm a diagnosis.

Upper right abdomen

Possible causes include:

  • gallstones;
  • liver disease; and
  • gallbladder infection.

Upper middle abdomen

Possible causes include:

  • gastritis;
  • peptic ulcer; and
  • pancreatitis.

Lower right abdomen

Possible causes include:

  • appendicitis;
  • kidney stones; and
  • ovarian problems.

Lower left abdomen

Possible causes include:

  • diverticulitis; and
  • constipation.

Pain across the whole abdomen

Possible causes include:

  • intestinal obstruction;
  • gastroenteritis; and
  • peritonitis.

Warning signs

Seek urgent medical care.

Severe or sudden pain, persistent vomiting, fever, blood in the stool or vomit, a swollen abdomen, yellow eyes, difficulty breathing, or fainting require prompt medical attention.

How abdominal pain is assessed

A doctor may use:

  • medical history;
  • physical examination;
  • blood tests;
  • urine tests;
  • ultrasound;
  • CT scan; and
  • endoscopy when necessary.

The investigations selected depend on the symptoms and clinical assessment.

Never ignore persistent pain

Pain lasting more than a few hours or worsening over time should be assessed by a doctor.

Take Home Message

Persistent or worsening abdominal pain requires medical assessment, especially when accompanied by warning signs.

Clinical references and guidance

This patient information is consistent with general guidance published by:

  • World Society of Emergency Surgery
  • Society of American Gastrointestinal and Endoscopic Surgeons
  • National Institute for Health and Care Excellence
  • American College of Surgeons
  • World Health Organization
Clinical guidance should be interpreted by a qualified medical professional and may be updated over time. These organizations have not formally endorsed this article.
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